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. 2021 Nov 8;6(42):11502–11527. doi: 10.1002/slct.202103301

Scheme 9.

Scheme 9

Synthesis of Ivermectin [B1a (91) & B1b (92)] by catalytic hydrogenation of the cis‐22,23‐ double bond of the avermectin [B1a (89) & B1b (90)].