Table 2.

GRADE evidence profile of COVID‐19 studies

Outcome	No. of participants			Risk of bias	Inconsistency	Indirectness	Imprecision	Other considerations	Quality of evidence (Grade)	Relative effect
	Total no.	Intervention	Control
Mortality	2768	561	2207	No	No	Yes	No	None	Low ⊕⊕⊝⊝	MD = 66.1 (95% CI: 47.7–84.4)
Severity	3262	1013	2249	No	No	Yes	No	None	Low ⊕⊕⊝⊝	MD = 86.74 (95% CI: 67.7–105.7)

Abbreviations: CI, confidence interval; MD, mean difference.