Table 1.
Baseline characteristics of patients admitted with COVID‐19 and treated with steroid and remdesivir stratified by discharge date
| Patients who were discharged before February 17th, 2021, N = 769 | Patients who were discharged between February 18th, 2021 and March 30th, 2021, N = 802 | p value | |
|---|---|---|---|
| Age, (mean, SD), year | 66.3 (15.6) | 65.8 (16.0) | 0.57 |
| Male, n (%) | 462 (60.1) | 431 (53.7) | 0.013 |
| Race, n (%) | 324 (42.1) | 212 (26.4) | <0.001 |
| White | 101 (13.1) | 157 (19.6) | |
| African American | 138 (17.9) | 177 (22.1) | |
| Hispanic | 50 (6.5) | 85 (10.6) | |
| Asian | 156 (20.3) | 171 (21.3) | |
| Other | |||
| Comorbidities | |||
| Asthma, n (%) | 31 (4.0) | 50 (6.2) | 0.063 |
| COPD, n (%) | 38 (4.9) | 35 (4.4) | 0.67 |
| Hypertension, n (%) | 239 (31.1) | 273 (34.0) | 0.23 |
| Diabetes mellitus, n (%) | 153 (19.9) | 181 (22.6) | 0.22 |
| Chronic kidney disease, n (%) | 28 (3.6) | 39 (4.9) | 0.28 |
| Obstructive sleep apnea, n (%) | 28 (3.6) | 13 (1.6) | 0.019 |
| Obesity, n (%) | 60 (7.8) | 84 (10.5) | 0.081 |
| HIV, n (%) | 28 (3.6) | 13 (1.6) | 0.019 |
| Cancer, n (%) | 69 (9.0) | 61 (7.6) | 0.37 |
| Atrial fibrillation, n (%) | 44 (5.7) | 63 (7.9) | 0.12 |
| Heart failure, n (%) | 36 (4.7) | 43 (5.4) | 0.62 |
| Coronary artery disease, n (%) | 88 (11.4) | 91 (11.3) | 1.00 |
| Peripheral vascular disease, n (%) | 30 (3.9) | 33 (4.1) | 0.93 |
| Alcoholic/nonalcoholic liver disease, n (%) | 13 (1.7) | 13 (1.6) | 1.00 |
| Vitals | |||
| Temperature (mean, SD) | 38.1 [37.4, 39.0] | 37.8 [37.3, 38.7] | <0.001 |
| Heart rate | 93.0 [82.0, 106.0] | 95.0 [84.0, 107.0] | 0.14 |
| (mean, SD) | |||
| Respiratory rate (mean, SD) | 20.0 [18.0, 22.0] | 20.0 [18.0, 22.0] | 0.009 |
| Systolic blood pressure (mean, SD) | 131.0 [118.0, 146.0] | 129.0 [116.0, 145.0] | 0.035 |
| Diastolic blood | 74.0 [66.0, 84.0] | 75.0 [66.0, 83.8] | 0.90 |
| Pressure (mean, SD) | |||
| O2 saturation (mean, SD) | 88.0 [81.0, 91.0] | 88.0 [80.0, 91.0] | 0.92 |
| Laboratory data | |||
| White blood cell, K/μl (mean, SD) | 7.0 [5.2, 9.7] | 6.3 [4.8, 8.5] | <0.001 |
| Hemoglobin, g/dl (mean, SD) | 13.4 [12.2, 14.6] | 13.6 [12.3, 14.7] | 0.180 |
| Blood urea nitrogen, mg/dl (median [IQR]) | 17.0 [12.0, 24.0] | 17.0 [12.0, 25.0] | 0.82 |
| Creatinine, mg/dl (median [IQR]) | 0.90 [0.74, 1.19] | 0.95 [0.76, 1.23] | 0.074 |
| Lactate dehydrogenase, U/L (median [IQR]) | 384.5 [293.0, 499.0] | 392.5 [299.5, 530.0] | 0.23 |
| C‐reactive protein, mg/L (median [IQR]) | 88.2 [50.2, 148.7] | 85.1 [46.4, 142.2] | 0.30 |
| D‐Dimer, μg/ml (median [IQR]) | 1.02 [0.65,1.81] | 1.13 [0.67, 1.97] | 0.029 |
Abbreviations: APTT, activated partial thromboplastin time; COPD, chronic obstructive pulmonary disease; COVID‐19, coronavirus disease 2019; HIV, human immunodeficiency virus; IQR, interquartile range.