Table 2.

Delivery of antigens of different COVID‐19 vaccines

Vaccine type	Delivering multiple antigens	Delivering endogenous antigens	Delivering large quantity of antigens	Basic mode for production or delivery of antigens
RPV	×	×	√	Direct injection
IV	√	×	√ or ×	Direct injection
LAV	√	√	√	Translation of antigen‐encoding message RNA via virus replication in recipient cells
mRV	×	√	√	Translation of injected antigen‐encoding message RNA in recipient cells
VV	×	√	√ or ×	Translation of the message RNA transcribed from antigen‐encoding DNA sent into recipient cells by virus vectors

Abbreviations: IV, inactivated vaccine; LAV, live‐attenuated vaccine; mRV, message RNA vaccine; RPV, recombinant protein vaccine; VV, vector vaccine.