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. 2021 Sep 21;94(1):82–87. doi: 10.1002/jmv.27335

Table 3.

Reasons why the world should collaborate to accelerate the development of COVID‐19 live‐attenuated vaccines (LAVs)

Order Reason
1 Other vaccines have limited efficacy and limited production efficiency
2 LAVs have well defeated far more viruses for long than other vaccines
3 Most of the current human vaccines for viral diseases are safe LAVs
4 LAVs could be much cheaper and produced much faster than other vaccines
5 Safety of LAVs can be well guaranteed via animal experiments and clinical trials
6 Safety of LAVs can be better guaranteed with modern technologies
7 Safety of LAVs can be better guaranteed with novel administration routes
8 LAVs could block transmission of relevant viruses and their variants completely and thus inhibit virus mutation
9 LAVs could protect immunologically abnormal individuals better from a panorama view
10 COVID‐19 LAVs could save millions of more lives than other vaccines
11 Global collaboration could significantly accelerate the development of COVID‐19 LAVs