Figure 2. Associations Between Particulate Matter 2.5 μm or Less in Diameter (PM2.5) Exposure and Restricted Isotropic Diffusion.
Annual mean PM2.5 exposure is associated with increases in restricted isotropic intracellular diffusion (rN0) microarchitecture in specific white matter tracts of the left or right hemisphere. Spline plots reflect model-predicted values of rN0 associated with annual mean PM2.5 exposure, with all other model covariates held constant. Sagittal and coronal images of relevant white matter tracts are provided for reference and colored to match spline plots. A indicates anterior; CGH, cingulum hippocampal portion; FX, fornix; L, left hemisphere; P, posterior; R, right hemisphere; SLF, superior longitudinal fasciculus; and UNC, uncinate fasciculus.