Table 3.

Estimated subHazard ratios by gray and fine method (with adjustment for age and year of diagnosis) for the EBRT cohort versus the reference cohort prostatectomy.

	EBRT +/- HT(n)	Radical Prostatectomy(n)	sHRs (95%CI)	p-value
All Solid	6834	3644	1.24 (1.19-1.30)	<0.01*
1991-1996	1172	513	1.25 (1.12-1.40)	<0.01*
1998-2005	2941	1421	1.27 (1.18-1.36)	<0.01*
2008-2014	1735	1174	1.24 (1.14-1.35)	<0.01*
All hematological	949	610	1.03 (0.91-1.15)	0.672
1991-1996	145	74	1.09 (0.80-1.48)	0.605
1998-2005	407	256	0.94 (0.79-1.12)	0.481
2008-2014	254	189	1.09 (0.88-1.35)	0.436
Non-Pelvis	4834	2823	1.14 (1.08-1.20)	<0.01*
1991-1996	814	390	1.13 (0.99-1.29)	0.075
1998-2005	2034	1099	1.13 (1.04-1.23)	<0.01*
2008-2014	1271	913	1.17 (1.06-1.29)	<0.01*
Pelvis	2000	822	1.61 (1.47-1.76)	<0.01*
1991-1996	358	123	1.17 (1.34-2.10)	<0.01*
1998-2005	907	322	1.74 (1.52-2.00)	<0.01*
2008-2014	464	261	1.47 (1.24-1.74)	<0.01*
Bladder	1380	490	1.83 (1.63-2.05)	<0.01*
1991-1996	237	79	1.76 (1.33-2.31)	<0.01*
1998-2005	649	195	2.04 (1.71-2.44)	<0.01*
2008-2014	307	150	1.65 (1.33-2.05)	<0.01*
Rectum	550	312	1.20 (1.03-1.40)	0.023*
1991-1996	110	41	1.51 (1.01-2.27)	0.043*
1998-2005	225	122	1.14 (0.90-1.45)	0.281
2008-2014	145	104	1.16 (0.87-1.55)	0.323

*indicates statistically significant p-values; external beam radiotherapy with/without hormonal therapy (EBRT +/- HT); sub-hazard ratios (sHRs).

Numbers reflect the observed numbers of survivors experiencing the SPC event of interest.