Table 5.
Changes in the scores of sexual life quality (SLQ) questionnaire.
| Gender | Baseline | Day 60 | Product effect p-value | |||||
|---|---|---|---|---|---|---|---|---|
| Placebo (n = 58) | Low dose (n = 58) | High dose (n = 59) | Placebo (n = 58) | Low dose (n = 58) | High dose (n = 59) | |||
| Male | 1. Frequency of lovemaking | 43.8 ± 17.2 | 46.3 ± 17.3 | 42.4 ± 14.6 | 46.1 ± 13.8 | 59.7 ± 14.0*** | 63.8 ± 11.5*** | <0.0001 |
| 2. Duration of lovemaking | 42.9 ± 15.0 | 42.1 ± 10.5 | 39.3 ± 11.1 | 48.7 ± 11.3 | 63.9 ± 14.0*** | 62.1 ± 12.0*** | <0.0001 | |
| 3. Ease of insertion | 48.2 ± 11.1 | 49.5 ± 11.2 | 48.7 ± 12.4 | 52.2 ± 14.6 | 60.6 ± 12.4* | 60.7 ± 10.0** | 0.0106 | |
| 4. Ease of achieving orgasm | 49.6 ± 14.6 | 50.0 ± 17.3 | 47.8 ± 15.6 | 53.0 ± 13.6 | 62.0 ± 13.6* | 62.9 ± 14.2** | 0.0150 | |
| 5. Ease of initiating lovemaking | 52.2 ± 13.2 | 51.4 ± 20.0 | 49.6 ± 15.4 | 52.2 ± 11.1 | 64.4 ± 15.0*** | 62.9 ± 11.0*** | <0.0001 | |
| 6. Pleasure of anticipation | 50.0 ± 9.0 | 51.4 ± 17.8 | 52.2 ± 15.2 | 47.8 ± 13.8 | 63.0 ± 14.1*** | 68.3 ± 13.8*** | <0.0001 | |
| 7. Carefree feelings during lovemaking | 46.9 ± 11.1 | 45.8 ± 15.5 | 46.0 ± 10.8 | 53.9 ± 12.5 | 66.7 ± 15.9** | 66.1 ± 13.1** | 0.0013 | |
| 8. Pleasure of orgasm | 42.4 ± 10.9 | 39.4 ± 17.6 | 38.8 ± 12.9 | 50.0 ± 14.9 | 61.6 ± 14.7** | 62.1 ± 12.9** | 0.0018 | |
| 9. Overall pleasure of lovemaking | 43.8 ± 11.0 | 43.5 ± 18.1 | 42.0 ± 13.3 | 52.2 ± 13.0 | 63.0 ± 16.4** | 63.4 ± 13.6** | 0.0065 | |
| 10. Partner's overall pleasure of lovemaking | 46.9 ± 10.0 | 47.2 ± 17.1 | 46.0 ± 11.3 | 52.6 ± 12.2 | 59.7 ± 14.8* | 60.7 ± 12.1* | 0.0348 | |
| SLQ scale score (mean of item 1-10) | 46.7 ± 8.3 | 46.7 ± 12.1 | 45.3 ± 10.3 | 50.9 ± 9.9 | 62.5 ± 12.3*** | 63.3 ± 10.4*** | <0.0001 | |
| Female | 1. Frequency of lovemaking | 38.4 ± 19.8 | 36.3 ± 14.1 | 40.7 ± 17.7 | 36.5 ± 16.1 | 52.8 ± 15.2*** | 63.4 ± 16.0*** | <0.0001 |
| 2. Duration of lovemaking | 45.1 ± 21.1 | 43.3 ± 12.6 | 46.8 ± 18.0 | 47.0 ± 18.8 | 56.0 ± 19.4* | 61.2 ± 17.8** | <0.0001 | |
| 3. Ease of insertion | 46.4 ± 18.9 | 44.6 ± 9.7 | 46.8 ± 16.1 | 50.5 ± 18.2 | 57.4 ± 16.4 | 58.2 ± 16.8 | 0.0909 | |
| 4. Ease of achieving orgasm | 38.8 ± 17.8 | 40.0 ± 13.3 | 42.3 ± 13.2 | 42.0 ± 18.4 | 52.3 ± 15.1* | 53.9 ± 15.0* | 0.0240 | |
| 5. Ease of initiating lovemaking | 42.0 ± 17.1 | 42.5 ± 13.0 | 44.0 ± 13.6 | 46.5 ± 16.7 | 56.0 ± 17.5 | 64.7 ± 19.8*** | 0.0003 | |
| 6. Pleasure of anticipation | 49.1 ± 13.6 | 47.5 ± 10.1 | 46.4 ± 14.1 | 50.5 ± 16.3 | 52.8 ± 12.7 | 62.5 ± 19.2** | 0.0042 | |
| 7. Carefree feelings during lovemaking | 47.8 ± 18.0 | 47.1 ± 11.7 | 47.6 ± 13.9 | 50.5 ± 15.9 | 63.0 ± 20.9** | 67.7 ± 16.5*** | 0.0009 | |
| 8. Pleasure of orgasm | 42.9 ± 19.4 | 44.2 ± 13.8 | 45.6 ± 14.6 | 42.5 ± 14.9 | 56.0 ± 17.5*** | 59.5 ± 13.2*** | <0.0001 | |
| 9. Overall pleasure of lovemaking | 47.8 ± 18.7 | 46.7 ± 10.9 | 49.6 ± 14.2 | 49.5 ± 14.2 | 56.9 ± 16.7* | 59.1 ± 15.3* | 0.0372 | |
| 10. Partner's overall pleasure of lovemaking | 52.2 ± 20.7 | 50.8 ± 9.2 | 52.8 ± 14.7 | 52.5 ± 12.5 | 58.8 ± 16.6 | 59.1 ± 17.3 | 0.1797 | |
| SLQ scale score (mean of item 1-10) | 45.0 ± 15.1 | 44.3 ± 7.5 | 46.3 ± 11.9 | 46.8 ± 12.8 | 56.2 ± 12.5*** | 60.9 ± 12.7*** | <0.0001 | |
Data are mean ± SD. Product effect was evaluated by ANCOVA with stratification of gender. Post-hoc test with Bonferroni adjustment was applied to variables with significant group difference for further pair-wise group comparison at day 60.
*
P < 0.05,
**
P < 0.01, and
***
P < 0.001 compared with placebo group. Numbers in bold indicate statistical significance.