Table 2.
Cost data with minimum and maximum values adjusted for inflation to reflect values in 2019 U.S. dollars.
| Model Parameter | Baseline value (minimum-maximum) | References |
|---|---|---|
| Costs | ||
| IV-tPA | $7,518 ($7,217–$9,022) | (25, 26) |
| EVT | $15,714 ($15,085–$18,857) | (25, 26) |
| NCCT | $202 ($194–$242) | (1, 26, 27) |
| CTA ± CTP | $789 ($757–$947) | (1, 26, 27) |
| Acute-care cost | ||
| Acute care costs within first 90 days after stroke (excluding imaging, IVT and EVT) mRS 0-2 | $11,544 ($11,083–$13,853) | (26, 28, 29) |
| Acute care costs within first 90 days after stroke (excluding imaging, IVT and EVT) mRS 3-5 | $26,818 ($25,745–$32,181) | (26, 28, 29) |
| Acute care costs within first 90 days after stroke (excluding imaging, IVT and EVT) mRS 6 | $7,681 ($7,374–$9,217) | (26, 28, 29) |
| 90-day utilities | ||
| mRS 0-2 | 0.89 | (30, 31) |
| mRS 3-5 | 0.33 | (30, 31) |
| Lifetime discounted QALYs | ||
| mRS 0-2 | 12.89 | (32) |
| mRS 3-5 | 5.5 | (32) |
| Time of diagnostic tests, minutes | ||
| NCCT | 5.00 | (3) |
| CTA | 15.00 | (3) |
| CTA+CTP | 25.00 | (18) |
| CTAP (NCCT+CTA+CTP) | 25.00 | (18) |
| Interval between patients | 10.00 | (18) |
| Probabilities of transitioning to 90-day modified Rankin scale (mRS): standard-of-care imaging | ||
| mRS 0-2 | 48.1340248% | (17) |
| mRS 3-5 | 35.2481406% | (17) |
| mRS 6 | 16.6178346% | (17) |
| Probabilities of transitioning to 90-day modified Rankin scale (mRS): advanced imaging | ||
| mRS 0-2 | 48.9114442% | (17) |
| mRS 3-5 | 34.4948803% | (17) |
| mRS 6 | 16.5936755% | (17) |
Utilities values are average utility values for the group of patients with the corresponding 90-day mRS scores. Lifetime discounted QALYs are the expected quality adjusted life years of people having respective 90-day mRS scores. Time to perform each of the imaging procedure, and interval time between patients in the CT scanner.