Fig. 4.

Emergence of tyrosine kinase subgroups and families throughout diverse holozoan taxa. The detection of each tyrosine kinase subgroup and family defined in the constraint-based classification is shown across diverse holozoan taxa, including single-celled relatives of metazoa. Constraint-based tyrosine kinase subgroups and families are shown across the x-axis, and diverse holozoan taxa, and their evolutionary relationships are shown on the y-axis. Cells are marked black if one or more members of a subgroup or family could be detected within a given taxa. For more information, see supplementary file S2 and supplementary figure S7, Supplementary Material online.