Table 2.
Effect of real iTBS v/s sham iTBS on symptom severity.
| Measure | Timepoint | Real iTBSa Mean (SE) | Sham iTBSa Mean (SE) | F(df) (Group effect) | p (Group effect) | F(df) (Time effect) | p (Time effect) | F(df) (Group * Time effect) | p (Group * Time effect) |
|---|---|---|---|---|---|---|---|---|---|
| Scale for the Assessment of Negative Symptoms (SANS) | Baseline | 86.35 (2.5) | 84.89 (2.93) | 1.144 (1,62.39) | 0.289 | 31.604 (2,110.99) | <0.001 | 0.511 (2,110.98) | 0.602 |
| Day6 | 77.69 (2.5) | 73.72 (2.93) | |||||||
| Week6 | 76.4 (2.7) | 71.97 (3.0) | |||||||
| Scale for the Assessment of Positive Symptoms (SAPS) | Baseline | 5.24 (1.36) | 7.41 (1.6) | 1.246 (1,57.10) | 0.269 | 9.675 (2,105.74) | <0.001 | 0.082 (2,105.73) | 0.921 |
| Day6 | 2.64 (1.36) | 4.69 (1.6) | |||||||
| Week6 | 4.7 (1.45) | 6.2 (1.63) | |||||||
| Calgary Depression Scale in Schizophrenia (CDSS) | Baseline | 1.17 (0.43) | 1.49 (0.49) | 0.074 (1,58.79) | 0.787 | 4.54 (2,106.34) | 0.013 | 1.913 (2,106.33) | 0.153 |
| Day6 | 0.34 (0.43) | 0.59 (0.49) | |||||||
| Week6 | 1.44 (0.48) | 0.48 (0.51) |
df = degrees of freedom, SE = standard error.
iTBS = intermittent theta burst stimulation.
p is significant at </=0.05
a
Estimated marginal means reported.