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. 2021 Nov 26;8:760989. doi: 10.3389/fsurg.2021.760989

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Copyright © 2021 Liu, Yang, Shi, Wen, Zhang, Wang, Hu, Shi, Cao, Guo and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protein and mRNA expression of pyroptosis-related molecules in control cohort and Z-YVAD-FMK-treated cohort. (A) mRNA expression of NLRP3, caspase-1, caspase-11, GSDMD, IL-1β, and IL-18 in rat kidney tissuses. (B) Western blotting results of NLRP3, pro-caspase-1, cleaved-caspase-1, cleaved-caspase-11, GSDMD, pro-IL-1β, cleaved-IL-1β and cleaved-IL-18. In rat kidney tissues. *p < 0.05, **p < 0.01. (n = 6 in each group). BD = brain-death; Sham = without brain death. GSDMD, gasdermin D; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.