Table 2.
Cord Blood Samples, Median and Interquartile Range of Respiratory Syncytial Virus (RSV)-A and RSV-B Neutralization (80% Inhibitory Concentration) by Group; P Values Comparing RSV Cases (All and Strain Specific) vs Controls
| Group | All Cases (N = 146) | Strain-specific Cases | ||
|---|---|---|---|---|
| Cord Blood IC 80 Median (IQR) | P Value (Wilcoxon) | Cord Blood IC 80 Median (IQR) | P Value (Wilcoxon) | |
| RSV-A IC80 levels | ||||
| RSV cases | 217 (128–377) | Ref | 219 (108–530) (n = 27) | Ref |
| ILI controls | 240 (137–453) | .22 | 240 (137–453) | .62 |
| Healthy controls | 256 (143–447) | .04 | 256 (143–447) | .32 |
| RSV-B IC80 levels | ||||
| RSV cases | 70 (41–159) | Ref | 72 (44–127) (n = 124) | Ref |
| ILI controls | 75 (44–156) | .47 | 75 (44–156) | .54 |
| Healthy controls | 88 (51–163) | .03 | 88 (51–163) | .04 |
Abbreviations: IC80, 80% inhibitory concentration; ILI, influenza-like illness; IQR, interquartile range; Ref, reference group; RSV, respiratory syncytial virus.
aILI controls and healthy controls were compared with RSV cases in unmatched preliminary analysis using nonparametric Wilcoxon rank sum tests.