Table 3.
Index Case and Household Characteristics by Whether Households Had Carbapenemase-Producing Enterobacterales–Colonized Household Contacts
Characteristic | Households With No CPE-Colonized Household Contacts (n = 79) | Households With at Least 1 CPE-Colonized Household Contacts (n = 16) | P Value |
---|---|---|---|
Index case characteristics | |||
Female sex, n (%) | 33 (42) | 4 (25) | .2 |
Age, median (IQR), years | 71 (46–77) | 70 (55–78) | .7 |
Charlson score of 3 or greater, n (%) | 21 (27) | 5 (31) | .7 |
Receipt of antibiotics in prior 6 months, n (%) | 70 (89) | 12 (75) | .2 |
Index case remaining CPE-colonized at enrollment, n (%) | 47 (60) | 14 (88) | .04 |
Travel in prior year (with/without hospitalization), n (%) | |||
Indian subcontinent | 53 (67) | 15 (94) | .07 |
Other countries (except United States/Northern Europe) | 10 (13) | 1 (6) | |
None or United States/Northern Europe | 16 (20) | 0 (0) | |
Hospitalization in prior year, n (%) | |||
Outside Canada | 50 (63) | 9 (56) | .6 |
In Canada | 21 (27) | 4 (24) | |
None | 8 (10) | 3 (19) | |
CPE species, n (%) | |||
Escherichia coli | 51 (65) | 10 (63) | .7 |
Klebsiella pneumoniae | 19 (24) | 5 (31) | |
Other | 9 (11) | 1 (6) | |
Carbapenemase produced, n (%) | |||
NDM | 47 (59) | 8 (50) | .6 |
OXA-48–like | 21 (27) | 7 (44) | |
NDM/OXA-48–like | 4 (5) | 1 (6) | |
KPC | 5 (6) | 0 (0) | |
VIM | 2 (3) | 0 (0) | |
Household characteristics | |||
Prestudy exposure to index case, median (IQR), days | 97 (51–225) | 86 (52–202) | .9 |
2 or more participating household contacts, n (%) | 28 (35) | 5 (31) | .7 |
Abbreviations: CPE, carbapenemase-producing Enterobacterales; IQR, interquartile range.