Table 2.
Variables Associated With 30-Day Mortality for Bloodstream Infections Only
| Variable | Dead (n = 85) |
Alive (n = 234) |
Univariate P Value |
Multivariate P Value |
aOR (95% CI) |
|---|---|---|---|---|---|
| Age, y, mean (SD) | 61.1 (13.6) | 58.3 (15.9) | .2113 | .239 | 1.01 (.99–1.03) |
| Charlson scorea, mean (SD) | 4.2 (3.2) | 3.2 (2.8) | .1705 | .039 | 1.11 (1.01–1.23) |
| Male sex | 37 (45.5) | 93 (39.7) | .543 | .325 | 0.75 (.42–1.34) |
| ICU residence | 60 (70.6) | 65 (27.8) | <.001 | <.001 | 7.32 (3.97–13.50) |
| Acinetobacter sppb | 10 (11.8) | 21 (8.8) | <.001 | .165 | 2.41 (.70–8.34) |
| Polymicrobial culture | 0 (0) | 2 (0.9) | .7311 | … | |
| Carbapenem-resistantc | 47 (55.3) | 122 (52.1) | .617 | .796 | 1.08 (.57–2.08) |
| History of transplantation | 18 (21.2) | 55 (23.5) | .559 | .021 | 0.39 (.18–0.87) |
| Cystic fibrosis | 0 (0) | 3 (1.3) | .294 | … | |
| Chronic kidney disease | 34 (40.0) | 79 (33.8) | .303 | .792 | 1.09 (.58–2.06) |
| Severe liver disease | 30 (21.6) | 39 (16.7) | <.001 | <.001 | 4.84 (2.23–10.49) |
Abbreviations: aOR, adjusted odds ratio; CI, confidence interval; ICU, intensive care unit; SD, standard deviation; spp, species.
aCharlson score adjusted for age and severe liver disease to avoid confounding.
bOdds of mortality calculated relative to carbapenem-resistant Escherichia coli.
cDefined as resistant, not including intermediate resistance, according to 2017 Clinical and Laboratory Standards Institute carbapenem breakpoints.