Table 4.
Hazard ratio of Parkinson’s disease associated with different types of age-related macular degeneration
| Variable | Parkinson’s disease | Crude HR (95%CI) | Adjusted HR (95%CI) | ||
|---|---|---|---|---|---|
| Event | PY | IR | |||
| Type of Age-related Macular Degeneration | |||||
| Unspecified AMD (ICD-9-CM code: 362.50) | |||||
| No | 326 | 64,236 | 5.08 | 1(reference) | 1(reference) |
| Yes | 382 | 51,939 | 7.35 | 1.45 (1.25–1.68)*** | 1.33 (1.14–1.54)*** |
| Non-neovascular AMD (ICD-9-CM code: 362.51) | |||||
| No | 634 | 107,589 | 5.89 | 1(reference) | 1(reference) |
| Yes | 74 | 8587 | 8.62 | 1.46 (1.15–1.86)** | 1.19 (0.94–1.52) |
| Neovascular AMD (ICD-9-CM code: 362.52) | |||||
| No | 666 | 110,575 | 6.02 | 1(reference) | 1(reference) |
| Yes | 42 | 5600 | 7.50 | 1.25 (0.91–1.70) | 1.09 (0.80–1.49) |
Abbreviations: aHR Adjusted Hazard Ratio estimated by the model including the variables of age-related macular degeneration, sex, age, osteoporosis, diabetes, cirrhosis, cerebrovascular disease, chronic kidney disease, hypertension, hyperlipidemia, coronary artery disease, chronic obstructive pulmonary disease, statin, and CCB, CCB Calcium Channel Blocker, CI Confidence Interval, HR Hazard Ratio, IR Incidence Rate, per 1000 person-years, PY Person-Years
*p < 0.05; **p < 0.01; ***p < 0.001