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. 2021 Mar 30;204(9):1075–1085. doi: 10.1164/rccm.202103-0660OC

Table 1.

Compounds Detected in Headspace of Airway Epithelial Cells That Differed between Medium- and RV-treated Cells

Retention Time (min)* P Value Q Value Log Change Compound M/Z Base Peak
9.27 0.000321 0.031275 1.0318 Poor match (MW = 48) 47
10.07 5.08 × 10−6 0.002312 −0.90847 2-Methyl-2-propanol 59
10.33 1.02 × 10−6 0.000696 −1.8906 Cyclobutylamine 43
10.33 4.08 × 10−5 0.009287 −1.0242 1-Chloro-2-methyl-butane 57
14.83 0.000252 0.026484 −0.55854 Poor match (MW = 119) 33
14.93 7.35 × 10−5 0.014336 −1.2767 Poor match (MW = 54) 39
19.42 0.000212 0.026306 0.49521 Dimethyl disulfide 94
19.47 7.71 × 10−5 0.013148 −2.2581 Acetoin 45
19.8 2.34 × 10−7 0.000319 −2.3047 Poor match (MW = 86) 56
26.69 3.19 × 10−5 0.008707 −0.90224 Poor match (MW = 250) 94
28.92 0.000171 0.023394 −0.8531 Decane 57
33.91 1.30 × 10−5 0.004427 −1.1848 Phenol acetate 94
43.24 0.000171 0.025977 1.4178 Poor match (MW = 270) 74
45.53 0.000212 0.024114 −1.1673 Poor match (MW = 366) 71

Definition of abbreviations: FDR = false discovery rate; M = mass; MS = M spectral; MW = molecular weight; NIST = National Institute of Standards and Technology; RV = rhinovirus; Z = charge number of ions.

Data were analyzed by using ANOVA with FDR correction (Q value). Negative log-change values indicate compounds increased in RV- versus medium-treated cells.

*

Retention time indicates the time to compound identification that was spent by a solute in the gas chromatography column.

The M/Z base peak, which is used to identify compounds, is the tallest peak in the M spectrum that is due to an ion having the greatest relative abundance.

Indicates identification by matching to the NIST MS library and authentic standard.