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. 2021 Nov 19;8(4):e26612. doi: 10.2196/26612

Table 5.

Treatment groups and primary outcome results of the included studies (N=12).

Study Intervention group Control group Primary outcome resultsa
Bailey et al [34] Hinge Health Digital Care Program, including a new tablet, 2 Bluetooth wearable motion sensors, and one-on-one remote health coaching; treatment as usual No control group VASbc
Priebe et al [28] GPd-centered LBPe treatment: 1. Electronic case report form; 2. Treatment algorithm for guideline-based clinical decision-making of GPs; 3. Teleconsultation between GPs and pain specialists for patients at risk for chronic back pain; 4. Kaia app Treatment as usual with consideration of the National guideline for the treatment of nonspecific back pain NRSf ↑ (↑)g
Hou et al [29] Patients with LBP who underwent lumbar spinal surgery were provided with a mobile phone–based eHealth program app as part of their rehabilitation program Nonspecific usual care rehabilitation treatment VAS ↑ (↑); ODIh ↑ (↑)
Shebib et al [30] Hinge Health Digital Care Program, including a new tablet, 2 Bluetooth wearable motion sensors, and one-on-one remote health coaching; treatment as usual A total of 3 digital education articles from the digital care program; treatment as usual MvKi (pain) ↑ (↑); MvK (disability) ↑ (↑); ODI ↑ (↑)
Toelle et al [31] Provided with the Kaia app A total of 6 individual physiotherapy sessions over 6 weeks and high-quality web-based education, including motivating messages NRS ↑ (↔j)g
Chhabra et al [32] Provided with the Snapcare app; written prescription from the physician (see Control group) Participants received a written prescription from the physician listing the prescribed medicines and dosage and stating the recommended level of physical activity NRS ↑ (↔); MODIk ↑ (↑)
Almhdawi et al [33] Provided with the Relieve my back app; treatment as usual Control group received a placebo version of the same app that included only advice about general nutrition and daily notifications with nutritional facts; treatment as usual VAS ↑ (↑); ODI ↑ (↑)
Lo et al [38] Retrospective evaluation study of the artificial intelligence–embedded Well Health app No control group NRS ↑
Huber et al [35] Retrospective analysis of user data: Kaia app users who signed up before March 2017 No control group NRS ↑
Clement et al [36] Retrospective analysis of user data: Kaia app users who signed up on or after May 1, 2017 Kaia app users who signed up before May 1, 2017 NRS ↑ (↑)
Priebe et al [37] Retrospective analysis of user data Kaia app users who signed up before March 2017 NRS ↑ (↑)
Sandal et al [39] Provided with the selfBACK app; treatment as usual No control group RMDQl

aMain result of the intervention group after the last measurement in the study.

bVAS: Visual Analog Scale.

cIntervention had positive effect compared with baseline measurement.

dGP: general practitioner.

eLBP: low back pain.

fNRS: Numeric Rating Scale.

gBetween-group differences are reported in parentheses.

hODI: Oswestry Disability Index.

iMvK: Modified von Korff Scale.

jNo difference in outcome.

kMODI: Modified Oswestry Disability Index.

lRMDQ: Roland Morris Disability Questionnaire.