Table 2.
Effects of quercetin and kaempferol on the weights of pups of rats exposed to postnatal food restriction at postnatal days (PNDs) 1, 14, 22 and at puberty.
| Treatment | Weight (g) at PND 1 | Weight (g) at PND 14 | Weight (g) at PND 22 | Pubertal weight (g) |
|---|---|---|---|---|
| Vehicle (10 mL/kg) | 4.85 ± 0.25 | 31.83 ± 2.20 | 37.17 ± 1.07 | 98.48 ± 2.50 |
| PsNFR Control | 4.78 ± 0.13 | 15.86 ± 1.41# | 19.13 ± 0.55# | 64.98 ± 4.33# |
| PsNFR + QCET (50 mg/kg) | 4.78 ± 0.22 | 23.43 ± 2.68 | 26.29 ± 2.47 | 84.87 ± 2.37 |
| PsNFR + QCET (100 mg/kg) | 4.88 ± 0.13 | 24.52 ± 2.55 | 32.77 ± 3.10∗ | 99.58 ± 7.19∗ |
| PsNFR + QCET (200 mg/kg) | 4.75 ± 0.20 | 27.98 ± 2.07∗ | 32.10 ± 2.86∗ | 98.97 ± 5.43∗ |
| PsNFR + KFAM (50 mg/kg) | 5.02 ± 0.08 | 23.15 ± 1.74 | 23.52 ± 0.73 | 83.53 ± 4.12 |
| PsNFR + KFAM (100 mg/kg) | 4.68 ± 0.25 | 20.18 ± 2.35 | 34.21 ± 2.55∗ | 87.01 ± 8.02 |
| PsNFR + KFAM (200 mg/kg) | 4.87 ± 0.10 | 27.77 ± 3.10 ∗ | 34.83 ± 3.79∗ | 94.62 ± 5.06∗ |
Values represent the mean ± SEM of 6 animals per group. #P < 0.05 compared to vehicle group; ∗P < 0.05 compared to PsNFR control group (One-way ANOVA followed by Bonferroni's post-hoc test). PsNFR = Postnatal food restriction, QCET = Quercetin, KFAM = Kaempferol.