Table 3.
Effects of quercetin and kaempferol on the weights of pups of rats exposed to both prenatal and postnatal food restrictions at postnatal days (PNDs) 1, 14, 22 and at puberty.
| Treatment | Weight (g) at PND 1 | Weight (g) at PND 14 | Weight (g) at PND 22 | Pubertal weight (g) |
|---|---|---|---|---|
| Vehicle (10 mL/kg) | 4.92 ± 0.11 | 29.89 ± 1.53 | 37.37 ± 2.85 | 91.12 ± 0.83 |
| PrNFR + PsNFR Control | 3.18 ± 0.20# | 12.01 ± 1.52# | 17.30 ± 1.19# | 55.25 ± 4.45# |
| PrNFR + PsNFR + QCET (50 mg/kg) | 4.85 ± 0.11∗ | 10.92 ± 0.95 | 20.31 ± 1.27 | 59.24 ± 2.71 |
| PrNFR + PsNFR + QCET (100 mg/kg) | 4.95 ± 0.07∗ | 19.64 ± 1.49 | 24.15 ± 2.20 | 64.38 ± 2.04 |
| PrNFR + PsNFR + QCET (200 mg/kg) | 4.63 ± 0.18∗ | 25.28 ± 2.77∗ | 29.58 ± 3.04∗ | 84.16 ± 7.04∗ |
| PrNFR + PsNFR + KFAM (50 mg/kg) | 4.67 ± 0.23∗ | 15.95 ± 3.04 | 19.88 ± 0.48 | 59.68 ± 0.94 |
| PrNFR + PsNFR + KFAM (100 mg/kg) | 4.70 ± 0.23∗ | 24.80 ± 2.04∗ | 34.52 ± 2.10∗ | 73.66 ± 6.55 |
| PrNFR + PsNFR + KFAM (200 mg/kg) | 4.93 ± 0.10∗ | 26.10 ± 2.77∗ | 33.89 ± 3.35∗ | 102.0 ± 4.96∗ |
Values represent the mean ± SEM (n = 6). #P < 0.05 compared to vehicle group; ∗P < 0.05 compared to PrNFR-PsNFR control group (One-way ANOVA followed by Bonferroni's post-hoc test). PrNFR = Prenatal food restriction, PsNFR = Postnatal food restriction, QCET = Quercetin, KFAM = Kaempferol.