Fig. 4.

Photomicrographs of striatum stained for TH immunoreactivity (a) and quantitation of TH fiber density (b) following 6-OHDA with and without GDNF treatment illustrates a robust ability of GDNF to preserve dopaminergic fibers. Scale bars ​= ​500 ​μm Data are presented as mean ​± ​SEM % of TH-positive fibers relative to the intact, non-lesioned hemisphere of 8 animals per group. Multiple comparisons were based on significant main effects of treatment resulting from the ANOVA described in Results: ∗∗p<0.01.