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Role of growth factors
| Growth factor | Role |
|---|---|
| PDGF | Mitogen for fibroblasts and smooth muscle cells, promotes angiogenesis and collagen production |
| TGF-β | Increases collagen content |
| VEGF | Promotes angiogenesis |
| EGF | Promotes cell growth, differentiation, Angiogenesis, and collagen production |
| Pro and antiinflammatory cytokines (IL-4, IL-8, IL-13, IL-17) | Stimulate fibroblasts and collagen synthesis |
