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. 2021 Nov 26;12:774539. doi: 10.3389/fphar.2021.774539

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Copyright © 2021 Dai, Liu, Peng, Qu, Lin, Peng and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Entinostat attenuates histopathologic damage following SCI. The histopathologic damage was assessed 7 days following SCI by H&E staining. (A) Black arrows indicating the neutrophil infiltration and TUNEL staining. (B) Nuclei were stained with DAPI. Histogram analysis of the TUNEL-positive cell. Data are expressed as the mean ± SEM, n = 6. Scale bar: 25 μm *p < 0.05, vs. the sham + vehicle group; #p < 0.05, vs. the SCI + vehicle group.