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. 2021 Dec 10;7(50):eabk3521. doi: 10.1126/sciadv.abk3521

Fig. 2. +9.5 Ets motif mitigates lethality induced by chronic stress.

Fig. 2.

(A) Mice were given multiple doses of pI:C (10 mg/kg) or vehicle control as per Walter et al. (37). Treatment cycles were repeated every 56 days. (B) Survival [PBS: WT (n = 10), +9.5(Ets)−/− (n = 14); pI:C: WT (n = 14), +9.5(Ets)−/− (n = 20) from two experiments] (log-rank test). (C) Number of cells per single hindlimb. n = 5 to 10 per condition, Tukey’s multiple comparisons test. *P < 0.05, **P < 0.01, ***P < 0.001. (D) Representative hematoxylin and eosin (H&E) staining of femurs. Each panel represents a single mouse. Scale bars, 50 μm.