Table 1. Comparison of general characteristics of patients with peripheral artery disease and controlled or uncontrolled hypertension.
Variables | Controlled hypertension | Uncontrolled hypertension | p value | |
---|---|---|---|---|
Clinical and demographic variables | ||||
Male sex (%) | (53.6) | (46.4) | 0.130 | |
Age (years) | 65±10 | 69±8 | 0.001 | |
Ankle-brachial index | 0.60±0.19 | 0.57±0.16 | 0.245 | |
Body mass index (kg/m²) | 28.0±4.9 | 27.4±4.7 | 0.342 | |
Claudication distance (m) | 133±85 | 125±68 | 0.465 | |
Six-minute walk test (m) | 326±91 | 318±85 | 0.531 | |
Systolic blood pressure (mmHg) | 121±12 | 158±15 | <0.001 | |
Diastolic blood pressure (mmHg) | 69±10 | 78±10 | <0.001 | |
Comorbidities | ||||
Current smoker (%) | (42.9) | (57.1) | 0.334 | |
Diabetes (%) | (48.4) | (51.7) | 0.633 | |
Dyslipidemia (%) | (53.2) | (46.8) | 0.056 | |
Obesity (%) | (52.6) | (47.4) | 0.642 | |
Coronary artery disease (%) | (55.6) | (44.4) | 0.241 | |
Stroke (%) | (56.1) | (43.9) | 0.806 | |
Medications | ||||
Antiplatelet | (51.2) | (48.8) | 0.949 | |
ACE inhibitor (%) | (64.9) | (35.1) | 0.018 | |
Angiotensin-receptor antagonist (%) | (48.4) | (51.6) | 0.579 | |
Calcium channel blocker (%) | (47.5) | (52.5) | 0.481 | |
Diuretic (%) | (45.5) | (54.5) | 0.152 | |
Beta-blocker (%) | (51.6) | (48.4) | 0.924 | |
Statin (%) | (53.2) | (46.8) | 0.137 | |
Hypoglycemic (%) | (47.7) | (52.3) | 0.371 | |
Peripheral vasodilator (%) | (58.5) | (41.5) | 0.219 | |
ACE inhibitor + diuretic + calcium channel blocker (%) | (53.8) | (46.2) | 0.904 |
Values expressed as median±interquartile range and frequency.
ACE: angiotensin conversion enzyme.