Table 3.
Comparison of Severity of COVID-19 Infection Between Diabetic and Control Group
| Severity of COVID-19 | Diabetic Group Number=197 | Non Diabetic or Hyperglycemic (Control Group) Number = 181 | P-value | |
|---|---|---|---|---|
| Severity | Mild - Moderate | 18 (9.1%) | 72 (39.8%) | < 0.0001 |
| Severe | 43 (21.8%) | 35 (19.3%) | ||
| Critical | 136 (69%) | 74 (40.9%) | ||
| Criteria | Mild-Moderate | |||
| No pneumonia on chest x-ray | 29 (14.7%) | 70 (38.7%) | <0.0001 | |
| No O2 requirement | 33 (16.8%) | 80 (44.2%) | <0.0001 | |
| Severe | ||||
| Respiratory rate>30/min | 32 (16.2%) | 27 (14.9%) | 0.7 | |
| Oxygen saturation <93% on room air | 56 (28.4%) | 46 (25.4%) | 0.5 | |
| PaO2/FiO2<300 | 1 (0.5%) | 1 (0.6%) | 0.9 | |
| Lung infiltrates >50% of lung field within 24–48 hours |
41 (20.8%) | 28 (15.5%) | 0.2 | |
| Critical | ||||
| Adult respiratory distress syndrome | 62 (31.5%) | 23 (12.7%) | <0.0001 | |
| Sepsis | 18 (9.1%) | 5 (2.8%) | 0.01 | |
| Altered level of consciousness | 21 (10.7%) | 4 (2.2%) | 0.001 | |
| Multi organ failure | 13 (6.6%) | 1 (0.6%) | 0.002 | |
| Cytokine Storm Syndrome: Ferritin>600ug/L at presentation and LDH>250 U/L | 63 (32%) | 42 (23.2%) | 0.057 | |
| Cytokine Storm Syndrome: D-Dimer > 1 mcg/mL | 79 (40.1%) | 38 (21%) | <0.0001 | |
Abbreviations: PaO2, partial pressure of oxygen; FiO2, fraction of inspired oxygen; LDH, lactate dehydrogenase.