Table 4.
The Association Between Severity of COVID-19 Infection with Baseline Characteristics and Comorbidities; a Univariate and Multivariate Analysis
| Univariate Analysis | P-values | Multivariate Analysis | ||||||
|---|---|---|---|---|---|---|---|---|
| Mild-Moderate (n = 94) |
Severe (n = 83) |
Critical (n = 237) |
Severe | Critical | ||||
| OR (95% CI) | P-value | OR (95% CI) | P-values | |||||
| Age | ||||||||
| Median (IQR) | 40.5 (32–54) | 52 (53–62) | 56.5 (46–65) | <0.0001 | 1.04 (1.02 −1.07) | <0.001 | 1.05 (1.03–1.08) | <0.001 |
| Gender | ||||||||
| Male (n =292) | 61 (20.9%) | 49 (16.8%) | 182 (62.3%) | 0.004 | *0.99 (0.5–1.93) | 0.97 | 3.07 (1.64–5.73) | <0.001 |
| Female (n =122) | 33 (27%) | 34 (27.9%) | 55 (45.1%) | |||||
| Hypertension | 21 (22.3%) | 26 (31.3%) | 103 (43.5%) | 0.001 | 0.58 (0.25 −1.35) | 0.21 | 0.94 (0.45–1.95) | 0.86 |
| Chronic kidney disease | 2 (2.1%) | 2 (2.4%) | 29 (12.2%) | 0.001 | 0.87 (0.11 −6.98) | 0.89 | 5.4 (1.11 −26.21) | 0.04 |
| Cardiac disease | 10 (10.6%) | 14 (16.9%) | 31 (13.1%) | 0.47 | 1.06 (0.38 −2.93) | 0.91 | 0.48 (0.19–1.24) | 0.13 |
| Hematologic disease | 5 (5.3%) | 5 (6%) | 11 (4.6%) | 0.88 | 2.74 (0.66–11.32) | 0.16 | 3.52 (1.01 −12.31) | 0.05 |
| Gastrointestinal disease | 2 (2.1%) | 1 (1.2%) | 7 (3%) | 0.66 | 0.54 (0.04–6.82) | 0.64 | 1.14 (0.17–7.49) | 0.89 |
| Rheumatologic disease | 3 (3.2%) | 0 (0%) | 4 (1.7%) | 0.259 | NA | – | 0.9 (0.5–2) | 0.7 |
| Diabetes Mellitus | 18 (9.1%) | 43 (21.8%) | 136 (69%) | <0.0001 | 3.61 (1.72–7.57) | <0.001 | 4.32 (2.2–8.3) | <0.001 |
Note: *Multivariate analysis was done for male gender since it was statistically associated with severity in univariate analysis.
Abbreviations: n, number; IQR, interquartile range.