Table 3.
Association Between Sustained Viral Response and Adherence Patterns Adjusted for Planned Treatment Weeks and Study Arms Among 113 Participants Treated With Combination Direct-Acting Antivirals
| Adherence Pattern | Exact Adjusted Odds Ratio for Sustained Viral Response | 95% Confidence Interval | P Value |
|---|---|---|---|
| Total dose | 1.12 | 1.04–1.22 | .002 |
| Weeks 1–4 | 1.25 | 1.04–1.59 | .015 |
| Weeks 5–8 | 1.31 | 1.09–1.79 | .001 |
| Weeks 9–12a | 1.12 | .92–1.45 | .293 |
| Percent total dose | 1.09 | 1.03–1.16 | <.001 |
| Days on treatment | 1.16 | 1.05–1.32 | .002 |
| Maximum consecutive adherent dose | 1.34 | 1.06–2.04 | .004 |
| Maximum consecutive missed dose | 0.85 | .74–.95 | .003 |
| Switches between adherent and missed doses | 1.01 | .91–1.13 | 1.000 |
aN = 82. The statistical results are obtained for applications of multivariable exact logistic regression models.