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. 2021 Dec 3;2021:5338182. doi: 10.1155/2021/5338182

Table 1.

Targets of tiger bone's main ingredients.

Main ingredients Uniprot ID Protein Gene symbol
Calcium phosphate P41180 Extracellular calcium-sensing receptor CASR
P27797 Calreticulin CALR
Q99828 Calcium and integrin-binding protein 1 CIB1
O75340 Programmed cell death protein 6 PDCD6
P30626 Sorcin SRI
Q99653 Calcineurin B homologous protein 1 CHP1
P09486 SPARC SPARC
P27824 Calnexin CANX
P35556 Fibrillin-2 FBN2
P04271 Protein S100-B S100B
O14958 Calsequestrin-2 CASQ2
Q15493 Regucalcin RGN
Q9UBV8 Peflin PEF1
P06703 Protein S100-A6 S100A6
P13693 Translationally controlled tumor protein TPT1
O75838 Calcium and integrin-binding family member 2 CIB2
Q99584 Protein S100-A13 S100A13
P31415 Calsequestrin-1 CASQ1
Q02818 Nucleobindin-1 NUCB1
P80303 Nucleobindin-2 NUCB2
P0DP23 Calmodulin CALM1
Q75N90 Fibrillin-3 FBN3
P28676 Grancalcin GCA
Q9ULU8 Calcium-dependent secretion activator 1 CADPS
P0DP24 Calmodulin-2 CALM2
P0DP25 Calmodulin-3 CALM3
Q96FQ6 Protein S100-A16 S100A16
P22676 Calretinin CALB2
Q13938 Calcyphosin CAPS
Q86UW7 Calcium-dependent secretion activator 2 CADPS2
Q96L12 Calreticulin-3 CALR3
Q9ULB1 Neurexin-1 NRXN1
P62166 Neuronal calcium sensor 1 NCS1

Magnesium phosphate No ID No protein No target
Osseocolla No ID No protein No target
Fat No ID No protein No target