Table 1.
Demographics and clinical measures of patients with mild cognitive impairment (MCI) and healthy controls (HC).
| HCs (n = 23) | MCI-highEF (n = 11) | MCI-lowEF (n = 14) | F(χ2) | P | |
|---|---|---|---|---|---|
| Age (years) | 60.96 ± 9.45 | 60.00 ± 6.68 | 70.00 ± 7.47b, c | 6.27 | 0.004* |
| Gender (M/F), n | 8/15 | 2/9 | 4/10 | 1.00 | 0.608 |
| Education (years) | 12.70 ± 2.24 | 12.18 ± 2.32 | 10.68 ± 3.16 | 2.75 | 0.075 |
| MMSE | 28.430 ± 1.56 | 27.73 ± 1.01 | 26.36 ± 1.45b, c | 9.30 | <0.001* |
| MoCA | 26.65 ± 1.70 | 23.91 ± 1.70 | 22.21 ± 2.46a, b, c | 9.30 | <0.001* |
| ADNI-EF | -0.11 ± 0.36 | −0.33 ± 0.18 | −1.60 ± 0.20a, b, c | 121.81 | <0.001* |
Data is represented by mean ± SD unless otherwise indicated. M, male; F, female; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment.
*
Significant differences were found among HC, MCI-highEF, and MCI-lowEF subjects. Most p-values were obtained using ANOVA, except for gender (chi-square test). Comparisons of each paired group were conducted to further reveal the source of ANOVA difference (a: MCI-highEF vs. HCs; b: MCI-lowEF vs. HCs; c: MCI-lowEF vs. MCI-highEF).