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. 2021 Nov 26;12:788870. doi: 10.3389/fmicb.2021.788870

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Copyright © 2021 Li, Ma, Wu, Niu, Li, Li, Xie, Idris and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic illustration of HSP27 as a molecular chaperone that stabilizes melanoma differentiation-associated gene 5 (MDA5) expression and positively regulates the type I IFN signaling pathway triggered by encephalomyocarditis virus (EMCV).