. 2021 Nov 22;8:779413. doi: 10.3389/fmed.2021.779413

Table 3.

Comparison of the circulating level of VEGF-A, VEGF-C, VEGF-D, and PlGF in all patients with abnormal and normal TC, LDL, TG, and HDL.

		VEGF-A	VEGF-C	VEGF-D	PlGF
		(pg/ml)	(pg/ml)	(pg/ml)	(pg/ml)
TC:
	Normal TC group	22.45 (17.09–32.30)	77.16 (43.40–125.32)	201.47 (122.13–335.91)	2.14 (0.99–3.10)
	Abnormal TC group	27.64 (19.86–37.45)	122.65 (61.12–219.99)	266.55 (142.79–427.94)	2.84 (1.78–3.66)
	z	−2.66^b	−3.31^b	−2.11^b	−2.87^b
	P-value	0.008^*	0.001^*	0.035^*	0.004^*
LDL-C:
	Normal LDL-C group	22.77 (17.41–32.30)	78.50 (42.61–128.59)	196.32 (102.48–335.91)	2.14 (1.00–3.13)
	Abnormal LDL-C group	27.64 (19.33–37.06)	118.52 (55.69–212.44)	266.55 (178.27–433.74)	2.84 (1.69–3.66)
	z	−2.14^b	−2.77^b	−2.36^b	−2.74^b
	P-value	0.032^*	0.006^*	0.018^*	0.006^*
TG:
	Normal TG group	24.85 (18.59–34.20)	82.65 (46.90–140.71)	245.08 (128.21–395.90)	2.47 (1.34–3.28)
	Abnormal TG group	24.49 (16.68–32.01)	115.51 (48.03–207.07)	209.77 (121.46–361.79)	1.85 (1.31–3.51)
	z	−0.84^b	−1.48^b	−0.51^b	−0.74^b
	P-value	0.400	0.140	0.610	0.458
HDL-C:
	Normal HDL-C group	24.85 (17.76–33.56)	99.82 (47.23–186.00)	227.54 (110.30–405.02)	2.41 ± 1.34
	Abnormal HDL-C group	24.86 (18.06–33.30)	81.95 (46.60–117.01)	233.87 (136.74–363.15)	2.33 ± 1.17
	t/z	−0.29^b	−0.99^b	−0.10^b	−0.37^a
	P-value	0.772	0.321	0.921	0.712

VEGF, vascular endothelial growth; PlGF, placental growth factor; TC, cholesterol; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol.

Statistically significant: P ≤ 0.05. According to the type of data and the data distribution,

independent-sample t-test, and

Mann-Whitney U-test were applied.