Table 1.
Drug | MIC (µg/mL) | Interpretation |
---|---|---|
Fluconazole | 0.25 | WT |
Voriconazole | ≤0.008 | NA |
Isavuconazole | 0.016 | NA |
Anidulafungin | 0.12 | WT |
Amphotericin B | 0.5 | WT |
Abbreviations: MIC, minimum inhibitory concentration; NA,no breakpoints/epidemiological cutoff value (ECV) available; WT,wild-type.
Antifungal susceptibility testing was performed using Sensititre YeastOne susceptibility plates (Thermo Scientific) [23] for fluconazole, voriconazole, anidulafungin, and amphotericin B, and gradient diffusion test strip (Liofilchem) [24] for isavuconazole. The results are interpreted using Clinical and Laboratory Standards Institute [25] breakpoints or ECVs [26], where available.