Table 2.
Drug | MIC (µg/mL) | Interpretation |
---|---|---|
Fluconazole | 4 | SDD |
Voriconazole | 0.25 | I |
Isavuconazole | 0.012 | NA |
Anidulafungin | 0.12 | S |
Amphotericin B | 1 | WT |
Abbreviations: MIC, minimum inhibitory concentration; I,intermediate; NA,no breakpoints/epidemiological cutoff value (ECV) available; S,susceptible; SDD,susceptible dose dependent; WT,wild-type.
Antifungal susceptibility testing was performed using Sensititre YeastOne susceptibility plates (Thermo Scientific) [23] for fluconazole, voriconazole, anidulafungin, and amphotericin B, and gradient diffusion test strip (Liofilchem) [24] for isavuconazole. The results are interpreted using Clinical and Laboratory Standards Institute [25] breakpoints or ECVs [26], where available.