Table 4.
Blood tests results performed during the first 72 h of admission presented by groups according to the current presence and history of a depressive or extended adjustment disorder.
| No-disorder group N=1036 |
Remitted group N=325 |
Persistent group N=336 |
De novo group N=154 |
Significance | |
|---|---|---|---|---|---|
| Interleukin-6 (pg/mL), mean (SD) | 91.76 (211.66) | 69.37 (171.57) | 88.63 (169.45) | 170.13 (308.19) | Welch ANOVA F=5.017; p=.002 Games-Howell post-hoc correction: DE NOVO vs NO-DISORDER; p=.01 DE NOVO vs REMITTED; p=.001 DE NOVO vs PERSISITENT; p=.01 NO-DISORDER vs REMITTED; p=.21 NO-DISORDER vs PERSISTENT; p=.99 REMITTED vs PERSISTENT; p=.47 |
| Adjusted interleukin-6 (pg/mL), mean (SE) | 90.89 (6.49) | 76.98 (11.53) | 88.95 (11.52) | 159.21 (16.80) | ANOVA F=5.839; p=.001 Bonferroni post-hoc correction: DE NOVO vs NO-DISORDER; p=.001 DE NOVO vs REMITTED; p < .001 DE NOVO vs PERSISITENT; p=.003 |
| C Reactive Protein (mg/L), mean (SD) | 94.38 (89.09) | 76.63 (72.45) | 93.99 (80.86) | 125.66 (107.47) | Welch ANOVA F=10.186; p < .001 Games-Howell post-hoc correction: DE NOVO vs NO-DISORDER; p=.004 DE NOVO vs REMITTED; p < .001 DE NOVO vs PERSISITENT; p=.007 NO-DISORDER vs REMITTED; p=.002 NO-DISORDER vs PERSISTENT; p=.99 REMITTED vs PERSISTENT; p=.02 |
| Adjusted C Reactive Protein (mg/L), mean (SE) | 93.86 (2.68) | 81.51 (4.75) | 94.53 (4.75) | 117.67 (6.92) | Anova F=6.119; p < .001 Bonferroni post-hoc correction: DE NOVO vs NO-DISORDER; p=.008 DE NOVO vs REMITTED; p < .001 DE NOVO vs PERSISITENT; p=.04 NO-DISORDER vs REMITTED; p=.15 Remitted vs persistent; p=.30 |
Abbreviations: SD, standard deviation; SE, standard error.
Patients were categorized into four groups according to the history and the presence at admission of a depressive or an extended adjustment disorder: 1) The “No-Disorder Group” included patients with no history or current diagnosis at admission of depressive or extended adjustment disorder); the “Remitted Group” included patients with positive history but no current diagnosis at admission); “Persistent Group” (patients with positive history and current diagnosis at admission); and “De Novo Group” (patients with no history but current diagnosis at admission of depressive or extended adjustment disorder).
Comparisons between groups were made using a one-way Welch analysis of variance (ANOVA) with a Games-Howell post-hoc correction. Adjusted comparison by confusing variables (sex, age, medical disorders, body mass index and smoking status) used a Bonferroni post-hoc correction.