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. 2021 Nov 9;99(12):skab336. doi: 10.1093/jas/skab336

Table 5.

Model calculation of the lysine requirement (Lys) for growing pigs (Sire line 337 × Dan line Camborough, PIC) challenged with E. coli lipopolysaccharide2, depending on the determined efficiency of lysine utilization and different predictions for feed intake

Item Control Challenged
NDmaxT1, mg/ BWkg0.75/ d 3,524.7 2,077.8
NDmaxT, % 68 54
Protein deposition, g/d 136 64
Lys efficiency, bc-1 0.00003703 0.00005713
Lys requirement, mg/ BWkg0.75/d 1,994.83 949.16
Lys requirement, g/d 18.12 8.62
Optimal dietary lysine concentration
Feed intake3 g/d Digestible Lys, % Feed intake3 g/d Digestible Lys, %
1,100 1.29 981 0.69
1,000 1.42 893 0.76
900 1.58 803 0.84
800 1.77 714 0.94

1NDmaxT is the theoretical maximum nitrogen deposition.

2 E. coli lipopolysaccharide (LPS) was used to induce inflammatory response in challenged group. The challenge consisted of an initial LPS dose of 30 μg/ kg IM and subsequent dose of 33.6 μg/kg IM after 48 h. The control group received saline solution (0.9%, IM).

3The feed intake was calculated based on the recommendations of Rostagno et al. (2017) for pigs of 20 kg. Feed intake was adjusted for the challenged group, considering the 10.73% reduction in feed intake.