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. 2021 Dec 10;11:23796. doi: 10.1038/s41598-021-03142-w

Figure 3.

Figure 3

Effect of the ethanolic extract of D. esculentum on Aβ42 accumulation in Drosophila models as (A) flies expressing Aβ42 (chr.2) and (B) flies expressing Aβ42 (chr.3). AD-free flies (elav-Gal4) were cultured on a normal medium, while AD flies (Aβ42) were cultured on a medium containing deionized water (DI), 1% DMSO, 125 µg/mL and 250 µg/mL of D. esculentum and 10 µM donepezil for 28 days and then assayed for Aβ42 levels. Values are mean ± SD of three assays and statistical significance was analyzed against AD flies (DI) by one-way ANOVA followed by Tukey’s test. *, p < 0.05; **, p < 0.01; ***, p < 0.001.