Table 2.
Fold differences between the average LC50 values in different media for each cell type and isocyanate exposure type.
| Exposure | Cell type | Supplemented : Basal (unadj p-value, FDR) | Basal : HBSS+ (unadj p-value, FDR) | Supplemented : HBSS+ (unadj p-value, FDR) |
|---|---|---|---|---|
| HDI monomer | Fibroblasts | 3 × (3.3E−2, 3.4E−2) | 4 × (3.1E−3, 5.2E−3) | 11 × (8.0E−3, 1.1E−2) |
| HDI monomer | Keratinocytes | 2 × (3.1E−7, 2.1E−6) | 2 × (7.9E−3, 1.1E−2) | 4 × (4.4E−11, 1.2E−9) |
| HDI monomer | Melanocytes | 2 × (1.3E−4, 3.2E−4) | 3 × (13E−4, 3.2E−4) | 5 × (5.8E−8, 5.2E−7) |
| HDI isocyanurate | Fibroblasts | 2 × (1.8E−4, 4.1E−4) | 2 × (6.3E−3, 1.0E−2) | 4 × (3.8E−6, 1.6E−5) |
| HDI isocyanurate | Keratinocytes | 1 × (1.9E−1, 2.0E−1) | 1 × (2.9E−1, 2.9E−1) | 2 × (2.7E−2, 3.1E−2) |
| HDI isocyanurate | Melanocytes | 2 × (1.8E−3, 3.3E−3) | 2 × (2.5E−2, 3.7E−2) | 2 × (2.0E−4, 4.7E−4) |