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TOP2A and Ki67 IHC interpretation in new cut versus old cut slides
| Old cut Slides |
New Cut Slides | |||
|---|---|---|---|---|
| No/Low | High | Total | Kappa 95% CI |
|
| TOP2Aa | ||||
| No/Low | 4 | 2 | 6 | 0.57 (0.14, 1.00) |
| High | 1 | 8 | 9 | |
| Total | 5 | 10 | 15 | |
| Concordance 80% (in 12 of 15 pairs) | ||||
| Ki67b | ||||
| No/Low | 7 | 3 | 10 | 0.61 (0.24, 0.97) |
| High | 0 | 5 | 5 | |
| Total | 7 | 8 | 15 | |
| Concordance 80% (in 12 of 15 pairs) | ||||
Expression categories defined by combined score of IRS system
Expression categories defined by cutoff point of 10% positive cells
