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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Sex Transm Dis. 2021 Jul 13:10.1097/OLQ.0000000000001509. doi: 10.1097/OLQ.0000000000001509

Figure 4. MG characteristics in men with MG-NGU.

Figure 4.

(A) Distribution of wildtype (WT) and MRM-containing MG alleles in mono- and mixed-infection MG-NGU at the treatment visit. MRM were A2058G, A2058T, and A2059G. (B) Percentage of men with WT or MRM-MG who had microbiological cure (MC). (C) Treatment visit urine MG organism load in men with WT or MRM MG-NGU. (D) Urine MG organisms load in treatment and TOC visits from men with MC failure. (E) Treatment visit urine MG organism load in men with/without MC cure. (F) TOC visit urine MG load in men with/without clinical (CC) cure. The y-axis in panels C-E is Log10. Horizontal bars denote the median and the whiskers denote 95% CI. Significance was evaluated by Fisher’s Exact (B) Mann-Whitney U (C, E, F) or Wilcoxon sign-rank test (D). (G) Phylogenetic Analysis of MG infections (N = 18) from treatment and/or TOC visits. Reference strains are denoted by the black lines. MG infections are denoted as study number followed by visit number (1 = treatment, 2 = TOC visit). Red arrows denote participant 30, the only participant with a wildtype MG infection who had microbiological failure; branch separation suggests the treatment and TOC MG infections are distinct genotypes.