Table 3.
Association of clinical cure with microbiological and Gram stain cure in men with NGU treated with azithromycin
| Gram stain evaluation | Microbiological evaluation | |||||||
|---|---|---|---|---|---|---|---|---|
| Cured % (n/N) |
Failed % (n/N) |
crude OR (95% CI) |
P-value* | Cured % (n/N) |
Failed % (n/N) |
crude OR (95% CI) |
P-value* | |
| CT only | ||||||||
| Clinical cure | 79.5% (35/44) | 20.5% (9/44) | 6.5 (1.3–32.4) | 0.025 | 96% (42/44) | 4% (2/44) | 7.0 (0.8–59.4) | 0.107 |
| Persistent signs/sx | 37.5% (3/8) | 62.5% (5/8) | 75% (6/8) | 25% (2/8) | ||||
| MG only | ||||||||
| Clinical cure | 62.5% (5/8) | 37.5% (3/8) | 2.8 (0.4–21.0) | 0.619 | 62.5% (5/8) | 37.5% (3/8) | 1.8 (0.2–15.4) | 1 |
| Persistent signs/sx | 37.5% (3/8) | 62.5% (5/8) | 37.5% (3/8) | 62.5% (5/8) | ||||
| UU only | ||||||||
| Clinical cure | 71.4% (5/7) | 28.6% (2/7) | N/A | N/A | 100% (7/7) | 0 | N/A | N/A |
| Persistent signs/sx | 0 | 0 | 0 | 0 | ||||
| Mixed infections ^ | ||||||||
| Clinical cure | 100% (6/6) | 0% (0/6) | 117 (1.9–7060) | 0.005 | 50% (3/6) | 50% (3/6) | 3.0 (0.2–48.0) | 0.571 |
| Persistent signs/sx | 0% (0/4) | 100% (4/4) | 25% (1/4) | 75% (3/4) | ||||
| IU only | ||||||||
| Clinical cure | 87.5% (21/24) | 12.5% (3/24) | 7.0 (1.3–36.7) | 0.036 | N/A | N/A | N/A | N/A |
| Persistent signs/sx | 50% (6/12) | 50% (6/12) | N/A | N/A | ||||
Abbreviations: sx, urethritis symptoms
*
Fishers exact test was used to compute p-values.
^
Haldane-Anscombe correction was used for computing the OR where applicable.