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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: J Subst Abuse Treat. 2021 Jul 8;131:108565. doi: 10.1016/j.jsat.2021.108565

Table 3.

Predicted prevalence and prevalence ratioa of primary outcomes for transgender relative to non-transgender patients: Among all VA outpatients with unhealthy alcohol use use (AUDIT-C ≥ 5) and among VA outpatients with unhealthy alcohol use and a prior-year alcohol use disorder diagnosis

Transgender Non-Transgender Prevalence Ratio (PR) for Transgender Relative to Non-Transgender
% (95% CI) % (95% CI) PR (95% CI) p-value
AMONG ALL VA OUTPATIENTS WITH UNHEALTHY ALCOHOL USE (N=1,405,734)
Brief intervention within 14 days
 Model 1b 74.2 (70.9 – 77.4) 74.8 (73.0 – 76.5) 0.99 (0.96 – 1.03) 0.655
 Model 2c 75.0 (71.8 – 78.2) 74.7 (72.9 – 76.5) 1.00 (0.97 – 1.04) 0.823
 Model 3d 75.4 (72.2 – 78.5) 74.6 (72.9 – 76.4) 1.01 (0.98 – 1.04) 0.574
AUD specialty addictions treatment
 Model 1b 22.9 (19.9 – 25.8) 12.7 (11.4 – 13.9) 1.80 (1.62 – 2.01) <0.001
 Model 2c 18.8 (16.4 – 21.2) 12.7 (11.4 – 14.1) 1.48 (1.33 – 1.64) <0.001
 Model 3d 15.7 (13.7 – 17.7) 12.6 (11.4 – 13.8) 1.24 (1.12 – 1.37) <0.001
Any AUD medication
 Model 1b 26.0 (23.6 – 28.5) 16.4 (15.8 – 17.1) 1.58 (1.44 – 1.74) <0.001
 Model 2c 21.9 (19.9 – 23.9) 16.4 (15.9 – 16.9) 1.33 (1.22 – 1.46) <0.001
 Model 3d 19.0 (17.1 – 20.8) 16.3 (15.8 – 16.8) 1.16 (1.06 – 1.28) 0.002
Any alcohol-related care
 Model 1b 84.2 (81.5 – 87.0) 81.3 (79.9 – 82.7) 1.04 (1.01 – 1.07) 0.013
 Model 2c 83.8 (81.0 – 86.6) 81.3 (79.9 – 82.7) 1.03 (1.00 – 1.06) 0.040
 Model 3d 82.8 (80.0 – 85.5) 81.2 (79.8 – 82.6) 1.02 (0.99 – 1.05) 0.183
AMONG VA OUTPATIENTS WITH UNHEALTHY ALCOHOL USE AND A DOCUMENTED ALCOHOL USE DISORDER IN THE YEAR PRIOR TO POSITIVE ALCOHOL SCREENING (N=521,119)
Brief intervention within 14 days
 Model 1b 72.9 (68.7 –77.1) 75.1 (73.2 – 77.0) 0.97 (0.92 – 1.02) 0.233
 Model 2c 73.7 (69.5 – 77.8) 75.0 (73.1 – 76.8) 0.98 (0.94 – 1.03) 0.466
 Model 3d 74.8 (70.7 – 78.9) 75.0 (73.1 – 76.8) 1.00 (0.95 – 1.05) 0.937
AUD specialty addictions treatment
 Model 1b 51.1 (36.2 – 66.0) 35.9 (25.8 – 46.0) 1.42 (1.28 – 1.58) <0.001
 Model 2c 40.0 (31.5 – 48.4) 31.4 (25.2 – 37.5) 1.28 (1.16 – 1.40) <0.001
 Model 3d 36.8 (29.5 – 44.1) 30.7 (25.2 – 36.2) 1.20 (1.09 – 1.32) <0.001
Any AUD medication
 Model 1b 32.4 (28.8 – 36.0) 23.5 (22.7 – 24.3) 1.37 (1.23 – 1.54) <0.001
 Model 2c 28.8 (25.6 – 31.9) 23.5 (22.8 – 24.3) 1.22 (1.09 – 1.36) <0.001
 Model 3d 26.1 (23.3 – 29.0) 23.5 (22.8 – 24.2) 1.11 (1.00 – 1.24) 0.058
Any alcohol-related care
 Model 1b 88.0 (85.1 – 90.9) 86.4 (85.3 – 87.4) 1.02 (0.99 – 1.05) 0.225
 Model 2c 87.5 (84.6 – 90.3) 86.4 (85.3 – 87.4) 1.01 (0.98 – 1.04) 0.422
 Model 3d 87.4 (84.5 – 90.2) 86.4 (85.3 – 87.4) 1.01 (0.98 – 1.04) 0.456

AUD, alcohol use disorder; AUDIT-C, Alcohol Use Disorders Identification Consumption; PR, prevalence ratio; VA, Veterans Health Administration

a

From mixed-effects modified Poisson regression models with logarithm link and a random effect for VA facility, with robust standard errors

b

Adjusted for fiscal year in which AUDIT-C screen occurred

c

Adjusted for fiscal year in which AUDIT-C screen occurred, sex, age, race/ethnicity, VA copay status, and marital status

d

Adjusted for fiscal year in which AUDIT-C screen occurred, sex, age, race/ethnicity, VA copay status, marital status, smoking status, Hepatitis C, HIV, Charlson score without HIV (categories 0, 1, ≥2); any mental health conditions, any non-alcohol SUD