Table I.

Differentially expressed genes related to 10 most statistically significant biological pathways identified by GO analysis for idiopathic AC

Biological pathway	Related genes
GO:0030049—muscle filament sliding	ACTA1, ACTC1, ACTN2, DES, MYBPC2, MYBPC1, MYH2, MYH7, MYL1, MYL2, MYL3, NEB, TTN, TCAP, TPM1, TPM2, TNNC1, TNNC2, TNNI1, TNNI2, TNNT1, TNNT3
GO:0006936—muscle contraction	ACTA1, ACTA2, ACTG2, CACNA1S, CKMT2, DES, DYSF, HRC, LMOD2, LMOD3, MYOM1, MYOM2, MYBPC2, MYH1, MYH2, MYH7, MYL1, MYLK, MYLPF, MYOT, TTN, TRDN, TRIM63, TPM1, TPM2, VIPR1
GO:0060048—cardiac muscle contraction	ACTC1, MYH7, MYL1, MYL2, MYL3, RYR2, SCN4B, TTN, TCAP, TPM1, TNNC1, TNNI1, TNNI2
GO:0030198—extracellular matrix organization	ACAN, COL1A1, COL1A2, COL3A1, COL5A1, COL5A2, COL5A3, COL11A1, COL16A1, EMILIN1, ELN, ITGA2, ITGA7, ITGA8, LOX, NDNF, NID1, NID2, OLFML2B, POSTN, SPARC
GO:0045214—sarcomere organization	LDB3, ACTN2, ANKRD1, CASQ1, FHOD3, KLHL41, LMOD2, OBSCN, TTN, TCAP, TPM1
GO:0030574—collagen catabolic process	COL1A1, COL1A2, COL3A1, COL5A1, COL5A2, COL5A3, COL6A5, COL11A1. COL18A1, MMP1, MMP13, MMP16, MMP3, MMP9
GO:0003009—skeletal muscle contraction	STAC3, MYH7, TCAP, TNNC1, TNNC2, TNNI1, TNNI2, TNNT1, TNNT3
GO:0030199—collagen fibril organization	ACAN, COL1A1, COL1A2, COL3A1, COL5A1, COL5A2, COL5A3, COL11A1, LOX, SERPINH1
GO:0007155—cell adhesion	ADAM12, NUAK1, THY1, ACTN2, ACAN, CDH11, COL1A1, COL5A1, COL6A5, COL16A1, COL18A1, EMILIN1, ITGA2, ITGA7, ITGA8, LRRN2, MYBPC2, MYBPC1, NCAM1, NID2, POSTN, PCDH17, RELN, SPON1, STAB2
GO:0007517—muscle organ development	CHODL, FHL3, HBEGF, ITGA7, MAPK12, MKX, MURC, NEB, SMTN, TAGLN, UNC45B

GO, Gene Ontology; AC, adhesive capsulitis.