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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: J Shoulder Elbow Surg. 2021 Aug 2;31(1):e1–e13. doi: 10.1016/j.jse.2021.06.016

Table II.

Differentially expressed genes related to 10 most statistically significant biological pathways identified by GO analysis for diabetic AC

Biological pathway Related genes
GO:0022617—extracellular matrix disassembly ADAMTS4, ACAN, MMP13, MMP9, SPP1
GO:0071376—cellular response to CRF stimulus NR4A1, NR4A2, NR4A3
GO:0007566—embryo implantation LIF, MMP9, PTGS2, SPP1
GO:0035914—skeletal muscle cell differentiation ATF3, EGR1, EGR2, NR4A1
GO:0048661—positive regulation of smooth muscle cell proLiferation AIF1, IL6, NR4A3, PTGS2
GO:0045444—fat ceU differentiation EGR2, NR4A1, NR4A2, NR4A3
GO:0046697—decidualization LIF, PTGS2, SPP1
GO:0045944—positive regulation of transcription from RNA Pol II promoter FOSL2, ATF3, CSRNP1, EGR1, EGR2, IL6, LIF, NR4A1, NR4A2, NR4A3
GO:0044344—cellular response to fibroblast growth factor stimulus EGR3, NR4A1, POSTN
GO:0006508—proteolysis ADAM12, ADAMTS1, ADAMTS4, ACAN, C1QA, MMP13, MMP9

GO, Gene Ontology; AC, adhesive capsulitis; CRF, corticotropin-releasing factor; Pol, polymerase.