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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Drug Alcohol Depend. 2021 Oct 28;229(Pt B):109137. doi: 10.1016/j.drugalcdep.2021.109137

Table 2:

Association between DSM-5 AUD and CUD and social and other problems (n = 35,650)

Disorders compared to non-disorder reference group Disorders compared to each other
AUD only vs. No AUD or CUD CUD only vs. No AUD or CUD AUD and CUD vs. No AUD or CUD CUD only vs. AUD only AUD and CUD vs. AUD only AUD and CUD vs. CUD only
Past Year Problems aORa
(95% CI)
aORa
(95% CI)
aORa
(95% CI)
aORa
(95% CI)
aORa
(95% CI)
aORa
(95% CI)
Interpersonal Problems
Trouble with boss or co-workers 1.87 (1.67–2.09) 1.41 (1.00–2.00) 2.83 (2.09–3.84) 0.76 (0.52–1.10) 1.51 (1.10–2.09) 2.00 (1.31–3.05)
Problems with neighbor, relative, friend 2.04 (1.79–2.31) 3.97 (2.65–5.94) 3.72 (2.91–4.75) 1.95 (1.28–2.96) 1.83 (1.40–2.39) 0.94 (0.58–1.50)
Broke up major relationship 2.37 (2.13–2.64) 2.42 (1.61–3.64) 4.01 (2.94–5.47) 1.02 (0.66–1.57) 1.69 (1.23–2.32) 1.66 (1.03–2.67)
Financial and Legal Problems
Fired or laid off 1.69 (1.46–1.95) 2.02 (1.37–2.99) 2.08 (1.53–2.83) 1.20 (0.83–1.73) 1.24 (0.90–1.70) 1.03 (0.66–1.61)
Unemployed 1.53 (1.38–1.70) 2.75 (2.12–3.57) 2.75 (2.15–3.52) 1.80 (1.40–2.32) 1.79 (1.40–2.31) 1.00 (0.70–1.43)
Homeless 2.78 (2.13–3.63) 4.26 (2.07–8.78) 4.28 (2.75–6.64) 1.53 (0.73–3.21) 1.54 (0.96–2.46) 1.00 (0.51–1.97)
Declared bankruptcy 1.04 (0.71–1.54) 1.28 (0.42–3.92) 1.66 (0.75–3.68) 1.22 (0.40–3.72) 1.59 (0.66–3.83) 1.30 (0.50–3.37)
So much debt couldn’t repay 1.90 (1.71–2.10) 2.33 (1.55–3.52) 2.79 (2.25–3.46) 1.23 (0.82–1.85) 1.47 (1.18–1.83) 1.20 (0.76–1.89)
Trouble with law/police 3.34 (2.59–4.31) 3.62 (2.20–5.95) 7.71 (5.27–11.27) 1.08 (0.63–1.86) 2.31 (1.57–3.39) 2.13 (1.11–4.08)
Health-related Problems
Hospitalized 1.13 (0.99–1.30) 0.79 (0.45–1.39) 1.92 (1.29–2.86) 0.70 (0.38–1.27) 1.70 (1.15–2.52) 2.43 (1.19–4.99)
Emergency treatment 1.29 (1.17–1.42) 1.74 (1.33–2.29) 1.92 (1.49–2.48) 1.35 (1.01–1.80) 1.49 (1.12–1.97) 1.10 (0.76–1.60)
Suicide attempt at current age 3.48 (1.60–7.59) 2.41 (0.31–18.74) 6.88 (2.48–19.04) 0.69 (0.06–7.66) 1.97 (0.56–6.92) 2.86 (0.53–15.45)
a

aOR= adjusted odds ratio; adjusted for age, sex, ethnicity/race, and education; 95% CI= 95% confidence interval. Note: Alcohol Use Disorder (AUD) and Cannabis Use Disorder (CUD) were defined by two or more use disorder DSM-5 criteria occurring in the past 12 months. Those with any other substance use disorder in the past year (n=659) were excluded from the analytic sample. Participants with missing responses an outcome were excluded for that analysis (range of missingness: 0.03%– 0.52%). The majority of missingness was among people with no AUD or CUD