Table 1.
Formulation | MNP: POx-Dopamine ratio | Feeding amount (mg) | Loading Efficiency (LE)1 (%) | Loading capacity (LC)2 (%) | |||||
---|---|---|---|---|---|---|---|---|---|
POx | POx-Dopamine | PTX | MNPs | PTX | MNPs | PTX | MNPs | ||
PTX-NFG/A | 1:4 | 8 | 2 | 2 | 0.5 | 106.9 | 67.5 | 17.1 | 2.7 |
PTX-NFG/B | 1:8 | 8 | 2 | 2 | 0.24 | 88.2 | 68.8 | 14.4 | 1.2 |
PTX-NFG/C | 1:40 | 8 | 2 | 2 | 0.05 | 95.8 | 72.3 | 15.9 | 0.3 |
PTX-NFG/D | 1:4 | 0 | 10 | 2 | 2.4 | 97.9 | 69.0 | 13.5 | 11.9 |
PTX-NFG/E | 1:8 | 0 | 10 | 2 | 1.2 | 100.0 | 71.0 | 15.1 | 6.7 |
PTX-NFG/F | 1:40 | 0 | 10 | 2 | 0.24 | 102.3 | 63.7 | 16.7 | 1.3 |
LE (wt. %) of either PTX (or MNPs) was calculated as the amount of PTX (or MNP) in final formulation/the feed amount of PTX (or MNP) X100.
LC (wt %) for either PTX or MNPs was calculated as the amount of PTX or MNPs in final formulation X100 / the amount of dispersed phase in the formulation.