Table 3.
Treatment | IC50 (ng/mL)a | ||
---|---|---|---|
MCF-7 | LCC-6-WT | LCC-6-MDR | |
PTX | 4.2 ± 2.7 | 6.6 ± 2.1 | 217 ± 76 |
PTX-NFG/A | 9.2 ± 2.8 | 7.5 ± 1.1 | 102 ± 14** |
PTX-NFG/B | 4.7 ± 1.9 | 6.2 ± 2.2 | 399 ± 202 |
PTX-NFG/C | 5.2 ± 4.4 | 15.8 ± 2.7 | 245 ± 50 |
PTX-NFG/D | 8.1 ± 7.7 | 4.2 ± 0.3 | 63 ± 22** |
PTX-NFG/E | 2.0 ± 1.5 | 5.3 ± 1.1 | 89 ± 37** |
PTX-NFG/F | 5.8 ± 1.3 | 1.7 ± 0.8 | 243 ± 24 |
Data represent mean ± S.D. (n=6).
P<0.01 compared to free PTX.