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Mean ± SD (n = 3) apparent ritonavir concentrations in the duodenal compartment of BioGIT (-•-) (reproduced from Van Den Abeele et al. 2020) and simulated ritonavir duodenal profiles using PBB modelling (- - -) assuming that one Norvir® tablet is administered under normal (a) and hypochlorhydric (b) gastric conditions.
