Table 1.
Age and Age-adjusteda characteristics of all participants (n=1618) at first blood collection in 1996–1999, Nurses’ Health Study 2.
| N (%) | AMH (ng/ml), Geometric Mean (SE) | ||
|---|---|---|---|
|
| |||
| Age (years) | |||
| 30–34 | 65 (4.0) | 2.5 (0.19) | |
| 35–39 | 803 (49.6) | 2.1 (0.05) | |
| 40–44 | 703 (43.4) | 0.7 (0.06) | |
| >45 | 47 (2.9) | 0.2 (0.22) | |
| White race | |||
| No | 59 (3.6) | 1.1 (0.20) | |
| Yes | 1559 (96.3) | 1.3 (0.04) | |
| Non-Hispanic ethnicity | |||
| No | 27 (1.7) | 1.0 (0.29) | |
| Yes | 1591 (98.3) | 1.2 (0.04) | |
| Body mass index (kg/m2) | |||
| <18.5 | 33 (2.0) | 1.5 (0.26) | |
| 18.5– <25 | 996 (61.5) | 1.3 (0.05) | |
| 25 – <30 | 358 (22.1) | 1.2 (0.08) | |
| ≥ 30 | 228 (14.1) | 1.0 (0.10) | |
| Body mass index at age 18 (kg/m2) | |||
| <18.5 | 220 (13.6) | 1.4 (0.10) | |
| 18.5– <25 | 1250 (77.2) | 1.2 (0.04) | |
| 25 – <30 | 108 (6.7) | 1.1 (0.14) | |
| ≥ 30 | 31 (1.9) | 1.1 (0.27) | |
| Age at menarche (yrs.) | |||
| 9 – 11 | 335 (20.7) | 1.0 (0.08) | |
| 12 | 508 (31.3) | 1.2 (0.07) | |
| 13 | 454 (28.0) | 1.4 (0.07) | |
| 14–17 | 321 (19.8) | 1.3 (0.08) | |
| Years until menstrual cycle became regular (yrs.) b | |||
| <1 | 765 (47.2) | 1.0 (0.05) | |
| 1 – 2 | 387 (23.9) | 1.1 (0.07) | |
| 3 – 4 | 131 (8.1) | 1.3 (0.13) | |
| ≥5 | 154 (9.5) | 1.5 (0.12) | |
| Smoking status | |||
| Never | 1166 (72.1) | 1.3 (0.04) | |
| Former | 326 (20.1) | 1.2 (0.08) | |
| Current | 126 (7.8) | 0.7 (0.13) | |
| Pack years of cigarette smoking | |||
| None | 1166 (72.1) | 1.3 (0.04) | |
| 1–5 | 169 (10.4) | 1.5 (0.11) | |
| 6–10 | 111 (6.9) | 1.0 (0.14) | |
| 11–15 | 80 (4.9) | 0.7 (0.17) | |
| 16–20 | 38 (2.3) | 0.9 (0.24) | |
| ≥21 | 53 (3.3) | 0.5 (0.21) | |
| Alcohol intake | |||
| None | 561 (34.7) | 1.3 (0.06) | |
| ≤5–6 drinks per week | 949 (58.6) | 1.2 (0.05) | |
| 1 drink per day | 59 (3.6) | 1.5 (0.20) | |
| 2– >6 drinks per day | 49 (3.0) | 1.1 (0.22) | |
| Physical activity (days per week) | |||
| <1 | 532 (32.9) | 1.2 (0.06) | |
| 1 | 371 (22.9) | 1.3 (0.08) | |
| 2 – 3 | 483 (29.8) | 1.2 (0.07) | |
| ≥4 | 232 (14.3) | 1.4 (0.10) | |
| Duration of oral contraceptive use (mo.) | |||
| Never | 306 (18.9) | 1.5 (0.09) | |
| 1–23 | 318 (19.6) | 1.3 (0.08) | |
| 24–71 | 528 (32.6) | 1.2 (0.06) | |
| 72–119 | 268 (16.7) | 1.1 (0.09) | |
| ≥120 | 173 (10.7) | 0.9 (0.11) | |
| Current exogenous hormone use | |||
| No | 1590 (98.3) | 1.3 (0.04) | |
| Yes | 28 (1.7) | 0.2 (0.28) | |
| History of infertility | |||
| None | 1258 (77.8) | 1.3 (0.04) | |
| Ovulatory | 121 (7.4) | 1.3 (0.14) | |
| Otherc | 238 (14.7) | 0.9 (0.10) | |
a
AMH levels were adjusted for age and age2
b
Percent sum does not equal 100 because participants whose menstrual cycle never became regular are not presented
c
Other causes for infertility include tubal blockage, endometriosis, cervical mucous factors, spouse/partner, infertility not investigated or unknown, other cause of infertility