Table 1.

Binding affinities of Diacerein with IL-6 (PDB:1N26). Comparative studies were performed using AutoDock 4.0.

Lead molecule	Target with PDB	Amino acids involved in Interactions	Affinity (kcal/mol)	H-bonds
Diacerein	IL-6 (PDB: 1N26)	LYS 45, GLY 73,PRO 46, ALA 47, SER 72, LEU 90, HIS 70, VAL 91, GLN 68, LEU 69, ASP 92, THR 124, LEU 123, VAL 93, SER 122	-8.4	2